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P2009
Development of a Non Binding Surface for Biochemical Assays & High-Throughput Screening
Presenter Rainer Heller, Greiner Bio-One, GmbH, Germany
Additional Authors: Claudia Kaiser, Ramona Gerwig, Heinrich Jehle
Low binding of proteins, peptides, DNA or RNA can be advantageous in sensitive biochemical assays. Consumables manufactured of polypropylene are often used for such applications because the resin is more chemically inert than other materials used in manufactures. However polypropylene surfaces still demonstrate minor biomolecule binding properties. To further reduce non-specific binding in critical assays, a new technology was developed to fabricate surfaces with ultra-low non-specific binding properties. This universal new technology can be used for the production of a wide variety of non-binding consumables for high-throughput screening, research and diagnostics.